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Molecular effects of protein alpha synuclein in the nucleus: DNA binding and transcriptional regulation
Protein alpha synuclein is involved in vesicular transport on synapses and regulation of dopamine release. There is the evidence that alpha-synuclein may play an important role in in Parkinson`s disease (PD) development but the mechanism by which alpha synuclein damages dopaminergic neurons remains elusive. As alpha synuclein is located in the nucleus of neurons and it has been shown that it binds…
Atbalstītāji
- Borovečki, Fran
Autors
- Gotovac, Kristina
Izdevējs
- University of Zagreb. Faculty of Science. Department of Biology.
Temats
- alpha synuclein
- transcriptional regulation
- Parkinson`s disease
- chromatin immunoprecipitation
- gene ontology
- NATURAL SCIENCES. Biology.
- Biochemistry. Molecular biology. Biophysics
Digitālais objekts veids
- info:eu-repo/semantics/doctoralThesis
- text
Datums
- 2014
- 2014
Atbalstītāji
- Borovečki, Fran
Autors
- Gotovac, Kristina
Izdevējs
- University of Zagreb. Faculty of Science. Department of Biology.
Temats
- alpha synuclein
- transcriptional regulation
- Parkinson`s disease
- chromatin immunoprecipitation
- gene ontology
- NATURAL SCIENCES. Biology.
- Biochemistry. Molecular biology. Biophysics
Digitālais objekts veids
- info:eu-repo/semantics/doctoralThesis
- text
Datums
- 2014
- 2014
Piegādājošā iestāde
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- http://rightsstatements.org/vocab/InC/1.0/
Identifikators
- https://dr.nsk.hr/islandora/object/pmf:1350
- https://urn.nsk.hr/urn:nbn:hr:217:426794
- https://repozitorij.unizg.hr/islandora/object/pmf:1350
- https://dr.nsk.hr/islandora/object/pmf%3A1350/datastream/TN/view/
Formāts
- application/pdf
Valoda
- hrv
Gads
- 2014
Nodrošinošā valsts
- Croatia
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- 2019-04-05T13:44:41.294Z
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- 2019-04-05T13:44:41.294Z