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Molecular effects of protein alpha synuclein in the nucleus: DNA binding and transcriptional regulation
Protein alpha synuclein is involved in vesicular transport on synapses and regulation of dopamine release. There is the evidence that alpha-synuclein may play an important role in in Parkinson`s disease (PD) development but the mechanism by which alpha synuclein damages dopaminergic neurons remains elusive. As alpha synuclein is located in the nucleus of neurons and it has been shown that it binds…
Contributeurs
- Borovečki, Fran
Créateur
- Gotovac, Kristina
Éditeur
- University of Zagreb. Faculty of Science. Department of Biology.
Thème
- alpha synuclein
- transcriptional regulation
- Parkinson`s disease
- chromatin immunoprecipitation
- gene ontology
- NATURAL SCIENCES. Biology.
- Biochemistry. Molecular biology. Biophysics
Type d'item
- info:eu-repo/semantics/doctoralThesis
- text
Date
- 2014
- 2014
Contributeurs
- Borovečki, Fran
Créateur
- Gotovac, Kristina
Éditeur
- University of Zagreb. Faculty of Science. Department of Biology.
Thème
- alpha synuclein
- transcriptional regulation
- Parkinson`s disease
- chromatin immunoprecipitation
- gene ontology
- NATURAL SCIENCES. Biology.
- Biochemistry. Molecular biology. Biophysics
Type d'item
- info:eu-repo/semantics/doctoralThesis
- text
Date
- 2014
- 2014
Institution partenaire
Agrégateur
Licence du support dans cet enregistrement (sauf indication contraire)
- http://rightsstatements.org/vocab/InC/1.0/
Identificateur
- https://dr.nsk.hr/islandora/object/pmf:1350
- https://urn.nsk.hr/urn:nbn:hr:217:426794
- https://repozitorij.unizg.hr/islandora/object/pmf:1350
- https://dr.nsk.hr/islandora/object/pmf%3A1350/datastream/TN/view/
Format
- application/pdf
Langue
- hrv
Année
- 2014
Pays fournisseur
- Croatia
Nom de la collection
Première publication sur Europeana
- 2019-04-05T13:44:41.294Z
Dernière mise à jour de l'Institution partenaire
- 2019-04-05T13:44:41.294Z