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Biliary amino acid excretion in rats before and after bilateral nephrectomy

In previous studies it could be shown that after bilateral nephrectomy (NX) the excretory function of the liver is disturbed. To further clarify whether or not this "renohcpatic syndrome" is caused by toxic effects of uremia or by competition phenomena between variuos uraemic toxins an additional aspect was investigated: the biliary excretion of endogenous amino acids. Furthermore, previously it c…