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Age-associated endothelial dysfunction in rat mesenteric arteries: roles of calcium-activated K+ channels (Kca)

Age-associated changes in large blood vessels were characterized by increased arterial wall thickness, luminal dilation and impaired endothelial function. But little is known about the effect of age on structural and functional changes in small resistance arteries. The mechanisms underlying age-associated endothelial dysfunction in rat mesenteric resistance arteries were investigated in the presen…